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近年来,关于硷腐蚀伤伤后反应,提出了胶原酶学说等新的概念,建立了抗胶原酶治疗的新方法,但疗效不够理想,目前对这类伤后组织的病理生理反应特性还不十分清楚。尽管已知前列腺素(Prostaglandin简称PG)参与了眼组织对多种外伤的伤性反应,但有关硷腐蚀伤的伤性反应的报告却极为少见。我们企图探讨眼组织对硷腐蚀伤反应的特性与变化规律,以求有助于提供有效的治疗方案,因此,我们测定了硷腐蚀伤后前房水中P G T与蛋白量的动态变化,并对消炎痛药膜在伤前或伤后应用的疗效与常用水冲洗法进行比较观察。
In recent years, a new concept of collagenase theory has been put forward in response to alkali corrosion injury, and a new method of anti-collagenase treatment has been established. However, the curative effect is not ideal enough. At present, the pathophysiological response to such wound tissue is not yet characterized Very clear. Although prostaglandin (PG) is known to be involved in the traumatic response of ocular tissues to a variety of traumatic injuries, the reports of traumatic reactions with alkalosis are extremely rare. We attempted to investigate the characteristics and changes of corneal alkali corrosion reaction in order to help to provide an effective treatment plan. Therefore, we measured the dynamic changes of PGT and protein in aqueous humor after alkaline corrosion, Pain film in the pre-injury or post-injury application of the efficacy of water washing method compared with the regular observation.