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作者在血脂门诊选择40例原发性高胆固醇血症患者为临床观察对象,这些病例排除了由疾患或药物、饮食等因素引起高胆固醇血症者。临床观察方法:所有受试者采用低脂低胆固醇饮食后,分3期:①病例选择期(1个月),2次测血清总胆固醇(TC)>6.5毫摩/升;②安慰剂期(35天),结束时TC<7.8毫摩/升18例,≥7.8毫摩/升22例;③美降脂期(3个月),第1个月时口服美降脂20毫克/日,第2个月
The author chooses 40 patients with primary hypercholesterolemia as the clinical observation object in the blood lipid clinic, and these cases exclude the patients with hypercholesterolemia caused by the diseases or drugs, diet and other factors. Clinical observation methods: All subjects were divided into three phases after low-fat and low-cholesterol diet: ① case selection period (1 month), 2 times serum total cholesterol (TC)> 6.5 mmol / L; ② placebo period (35 days), the end of TC <7.8 mmol / l in 18 cases, ≥ 7.8 mmol / l in 22 cases; ③ the United States lipid-lowering period (3 months), the first month of oral administration of lipid-lowering 20 mg / day , The second month