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DR抗原表达在绝大部分B淋巴细胞和某些单核细胞上,而外周血T淋巴细胞不表达这种表面标记物。一旦外周血中出现DRT细胞时,应考虑此免疫系统被激活。本文观察短程免疫抑制疗法对16例HBsAg~+慢性活动性肝炎(CAH)患儿DR~+T细胞百分比的影响。对象和方法16例随机抽样的乙型CAH患儿,年龄6～13岁。在开始观察时,全部患儿均无临床症状,而HBsAg均阳性。7例HBeAg~+,7例抗-HBeAg~+,9例血清抗-δ~+(delta)抗体。观察前全部患儿均未接受过免疫抑制治疗。可的松剂量为1mg/kg/d,口服共3日。对照组为10名年龄相似健康儿童。
DR antigen is expressed on most B lymphocytes and certain monocytes, whereas peripheral T lymphocytes do not express this surface marker. Once DRT cells appear in peripheral blood, the immune system should be considered to be activated. This article observes the effect of short-course immunosuppressive therapy on the percentage of DR ~ + T cells in 16 children with HBsAg + chronic active hepatitis (CAH). Subjects and methods 16 cases of randomly selected children with type B CAH, aged 6 to 13 years old. At the beginning of observation, all children had no clinical symptoms, while HBsAg were positive. 7 cases of HBeAg ~ +, 7 cases of anti-HBeAg ~ +, 9 cases of serum anti-δ ~ + (delta) antibody. All children before observation did not receive immunosuppressive therapy. Cortisone dose of 1mg / kg / d, orally for a total of 3 days. The control group was 10 healthy children of similar ages.