论文部分内容阅读
目的探究阻塞型睡眠呼吸暂停综合征的临床治疗方法及效果。方法将本院近两年收治的60例阻塞型睡眠呼吸暂停综合征患者作为观察对象,并按照随机分组的原则将所有患者分为治疗组和对照组,每组30例,对照组患者按照常规的方法进行治疗,治疗组患者在对照组治疗的基础上实施气道正压通气治疗,对比观察两组的治疗效果及血清IL-6和hs-CRP水平的变化。结果在治疗效果方面,治疗组患者的各症状缓解情况均明显优于对照组,组间差异具有显著性(P<0.05);治疗后两组患者血清IL-6和hs-CRP水平均与治疗前比较具有显著的降低,且治疗组的下降幅度明显高于对照组,组间差异具有显著性(P<0.05)。结论对于阻塞型睡眠呼吸暂停综合征患者在常规治疗的基础上实施气道正压通气治疗,能够显著改善症状,有效降低血清IL-6和hs-CRP水平,能够成为治疗该病的有效方法,并可在临床进行广泛的推广与应用。
Objective To explore the clinical treatment of obstructive sleep apnea syndrome and its efficacy. Methods Sixty patients with obstructive sleep apnea syndrome admitted in our hospital in recent two years were divided into treatment group and control group according to the principle of randomization. All patients were divided into treatment group (30 cases) and control group The patients in the treatment group were treated with positive airway pressure ventilation on the basis of the control group. The therapeutic effects and the changes of serum IL-6 and hs-CRP levels were compared between the two groups. Results In the treatment effect, the alleviation of symptoms in the treatment group was significantly better than that in the control group, the difference was significant (P <0.05); after treatment, the levels of serum IL-6 and hs-CRP Before comparison, there was a significant reduction, and the decline of treatment group was significantly higher than that of control group, the difference was significant (P <0.05). CONCLUSIONS: In patients with obstructive sleep apnea syndrome, performing positive airway pressure therapy on the basis of routine treatment can significantly improve the symptoms and effectively reduce the levels of serum IL-6 and hs-CRP, which can be an effective treatment for this disease. And can be widely used in clinical promotion and application.