目的了解新生儿是否具有母源性抗-HBs。方法观察77例生后24 h内新生儿,采集静脉血,进行抗-HBs定性检测,部分新生儿同时进行抗-HBs定量检测。结果 77例中,抗-HBs定性检测阳性40例,阳性率51.95%。在抗-HBs定性检测阳性40例中,有29例进行了抗-HBs定量检测,抗-HBs≥1 000 mIU/mL8人,抗-HBs(≥500 mIU/mL,<1 000mIU/mL)5人,抗-HBs(≥100 mIU/mL,<500 mIU/mL)9人,抗-HBs(≥10 mIU/mL,<100 mIU/mL)7人。结论新生儿会具有母源性抗-HBs。 Objective To understand if a newborn has maternal anti-HBs. Methods Totally 77 newborns within 24 hours after birth were collected and venous blood was collected for qualitative detection of anti-HBs. Some newborns were tested for anti-HBs at the same time. Results In 77 cases, qualitative detection of anti-HBs was positive in 40 cases, the positive rate was 51.95%. Among the 40 cases with positive anti-HBs test, 29 cases were tested for anti-HBs quantitatively, anti-HBs≥1000 mIU / mL8, anti-HBs (≥500 mIU / mL, <1 000 mIU / mL) Human, anti-HBs (≥100 mIU / mL, <500 mIU / mL) and anti-HBs (≥10 mIU / mL, <100 mIU / mL) Conclusion Neonates have maternal anti-HBs.