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为了探讨有氧运动和膳食因素在动脉粥样硬化斑块形成过程中的作用 ,研究了在跑台上进行的有氧运动和低脂膳食对ApoE基因缺陷小鼠动脉粥样硬化斑块形成过程的影响。结果表明 :10周中等强度的有氧运动组和低脂膳食组ApoE基因缺陷小鼠主动脉窦处形成的动脉粥样硬化斑块面积均较对照组减少 (P <0 0 5 ) ;有氧运动结合低脂膳食组ApoE基因缺陷小鼠的斑块面积分别低于单独的运动组和低脂膳食组 (P <0 0 5 )。研究提示有氧运动和低脂膳食均有利于并有效减轻动脉粥样硬化斑块的形成 ,有氧运动和低脂膳食两种因素结合的作用大于单独的有氧运动和低脂膳食的作用 ,二者在预防动脉粥样硬化斑块的形成上可能存在协同加强作用
In order to investigate the role of aerobic exercise and dietary factors in the formation of atherosclerotic plaque, the effects of aerobic exercise and low-fat diet on the formation of atherosclerotic plaque in ApoE-deficient mice Impact. The results showed that the area of atherosclerotic plaque formed in the aortic sinus in ApoE gene-deficient mice of 10-week moderate-intensity aerobic exercise group and low-fat diet group was lower than that of the control group (P <0.05) The area of plaque in ApoE-deficient mice with exercise-bound low-fat diet group was lower than that in exercise-only group and low-fat diet group (P <0.05). Research suggests that aerobic exercise and low-fat diet are beneficial and effective in reducing the formation of atherosclerotic plaque. The combination of aerobic exercise and low-fat diet is more effective than aerobic exercise and low-fat diet alone. The two may play a synergistic role in preventing the formation of atherosclerotic plaque