凝血因子Ⅺ(factorⅪ,FⅪ)缺陷症是一种遗传性出血病。FⅪ缺乏可引起凝血酶缺乏、纤溶亢进,从而引起出血增多。FⅪ缺陷症患者出血多发生于口腔、鼻腔黏膜等纤溶活性较高的部位,出血常与创伤及手术有关。本文报告1例中日友好医院近期诊治的病例,患者拔牙术后术区反复出血,给予碘仿砂条填塞方法止血控制病情,最终血液检查确诊患者罹患凝血因子Ⅺ缺陷症,通过血浆输入治疗,最终止血成功。 Factor XI (FXI) deficiency is a hereditary hemorrhagic disease. FXI deficiency can cause thrombin deficiency, fibrinolysis, resulting in increased bleeding. Bleeding in patients with FXI deficiency occurred in the mouth, nasal mucosa and other fibrinolytic activity of higher parts of the bleeding often associated with trauma and surgery. This paper reports a case of Sino-Japanese Friendship Hospital recently diagnosed and treated patients with repeated bleeding after operation, surgery to give iodoform sand filling method to control the disease, the final blood test confirmed patients suffering from factor Ⅺ deficiency, through the plasma input therapy, The final stop bleeding success.