淋巴瘤是发生于淋巴结和(或)结外淋巴组织的恶性肿瘤,是具有相当异质性的一大类肿瘤,随着分子生物学的不断发展,人们对淋巴瘤的发病机制、分类和预后等方面的认识也在不断的深入。同其他恶性增殖性疾病类似,淋巴瘤存在基因不稳定性,染色体异常是淋巴瘤发生发展的直接原因之一。体细胞获得性基因突变,通过破坏细胞周期中 Lymphoma is a malignant tumor that occurs in lymph nodes and / or extranodal lymphoid tissue. It is a very heterogeneous group of tumors. With the continuous development of molecular biology, the pathogenesis, classification and prognosis of lymphoma And other aspects of the understanding is constantly in-depth. Like other malignant proliferative diseases, lymphomas have genetic instability. Chromosomal abnormalities are one of the direct causes of the development of lymphoma. Somatic acquired genes mutate by disrupting the cell cycle