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目的研究柠檬酸钠的用量对重型肝炎血浆置换效果的影响。方法收集住院重型肝炎病例102人,根据柠檬酸钠的用量分为2组,A组比值1:9~10,46例,共84人次;B组比值1:12,56例,共102人次。结果A组存活24例(52.2%),B组46(82.2%),2组的副作用和肝功能改善差异有统计学意义(P<0.05)。结论柠檬酸钠量与置换血浆之比控制在较低水平可改善重型肝炎的预后。
Objective To study the effect of sodium citrate dosage on the plasma exchange efficiency of severe hepatitis. Methods Totally 102 inpatients with severe hepatitis were collected and divided into 2 groups according to the dosage of sodium citrate. The ratio of group A to group A was 1: 9-10,46, with a total of 84 persons. The ratio of group B to group B was 102: 56. Results A group of survival in 24 cases (52.2%), B group 46 (82.2%), two groups of side effects and improvement of liver function difference was statistically significant (P <0.05). Conclusion The lower level of sodium citrate and replacement plasma ratio can improve the prognosis of severe hepatitis.