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目的：为解决颅底恶性肿瘤的广泛切除或根治性切除术后所致的颅底骨与软组织缺损，预防此缺损所致的颅内感染，脑脊液漏等并发症。方法：在术中应用了斜方肌下部岛状肌皮瓣，胸大肌下部岛状肌皮瓣，颞肌复合组织瓣等各种修复方法分别对18例患者进行了一期修复。结果：修复成功率73．2％（13例），术后并发症27．8％（5例）.结论：根据组织缺损的不同大小、范围、程度、部位和不同的手术入路来选择不同的修复方法，关系到手术成败。
Objective: To solve the skull base tumor after radical resection or radical resection of the skull base and soft tissue defects, prevention of this defect caused by intracranial infection, cerebrospinal fluid leakage and other complications. Methods: A total of 18 patients undergoing primary repair were treated with various methods, including trapezius musculocutaneous flap, pectoralis major myocutaneous flap and temporal muscle flap. Results: The success rate of repair was 73.2% (13 cases) and postoperative complications was 27.8% (5 cases) .Conclusion: According to the different size, scope, degree, location and different surgical approach of tissue defect, The repair method, related to the success or failure of surgery.