论文部分内容阅读
目的 :探索慢性乙肝重叠戊肝病毒感染后其临床表现、肝功能及对 HBV的影响。 方法 :对 30例慢性乙肝重叠戊型肝炎病毒感染后对临床表现、肝功能以及 HBV复制指标 (HBe Ag、HBV- DNA)与单纯乙肝和戊肝病人进行对比观察。 结果 :发现慢性乙肝重叠戊型肝炎病毒感染后其临床类型偏中、重型多 ,与单纯慢性乙肝、戊肝血清总胆红素、AL T、AST比较明显增高。与单纯乙肝比较 ,HBe Ag和 HBV- DNA阳性率显著降低 ,经检验有统计学差异。结论 :慢性乙肝重叠戊肝病毒感染是引起原有慢性乙肝病情加重的原因之一 ,并对 HBV复制指标有抑制作用
Objective: To explore the clinical manifestations, liver function and HBV after chronic hepatitis E overlap hepatitis E virus infection. Methods: The clinical manifestations, liver function, HBsAg, HBV-DNA and hepatitis B and hepatitis E were observed in 30 patients with chronic hepatitis B overlap hepatitis E infection. Results: The clinical type of chronic hepatitis B overlapped hepatitis E virus was found to be moderately to moderately severe, and more severe than those of chronic hepatitis B and E liver. The serum total bilirubin, ALT and AST were significantly higher. Compared with the simple hepatitis B, HBeAg and HBV DNA positive rate was significantly reduced, the test was statistically significant. Conclusion: Chronic hepatitis B overlap hepatitis E virus infection is one of the causes of the exacerbation of chronic hepatitis B, and inhibit the HBV replication index