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目的:探讨沐舒坦(盐酸氨溴索注射液)治疗卧床的老年患者肺炎的临床疗效。方法:将2012年1月-2013年12月广东药学院附属第一医院收住的46例卧床的老年肺炎患者按系统抽样和分层抽样相结合分成两组,对照组23例,观察组23例。两组均使用抗生素,吸氧,支持对症等常规治疗,同时观察组给予沐舒坦150 mg静脉滴注,1次/d,观察两组患者的症状体征及血气改善情况并分析。结果:观察组(沐舒坦组)在治疗10 d后的临床有效率(91.3%)明显高于对照组(65.2%),临床疗效、血气分析指标等方面其治疗后都较治疗前有显著改善,差异具有统计学意义(P<0.05)。治疗期间两组患者均无严重的药品不良反应。结论:沐舒坦在卧床的老年肺炎患者中使用疗效确切,使用安全。
Objective: To investigate the clinical efficacy of ambroxol hydrochloride (ambroxol hydrochloride injection) in elderly patients with bed-ridden pneumonia. Methods: 46 elderly bedridden pneumonia admitted to the First Affiliated Hospital of Guangdong Polytechnic University between January 2012 and December 2013 were divided into two groups according to systematic sampling and stratified sampling. The control group (23 cases) and observation group (23 cases) example. The two groups were given antibiotics, oxygen, supporting symptomatic and other conventional treatment, while the observation group was given intravenous infusion of ambroxol 150 mg, 1 / d, observed two groups of patients with signs and symptoms and blood gas to improve the situation and analysis. Results: The clinical effective rate (91.3%) in the observation group (MuShuTan group) was significantly higher than that in the control group (65.2%) after 10 days of treatment. The curative effect and blood gas analysis index of the observation group were significantly improved after treatment , The difference was statistically significant (P <0.05). During the treatment of two groups of patients without serious adverse drug reactions. Conclusion: Mucosolvan is safe and safe to use in elderly patients with pneumonia in bed.