寻常性天疱疮是一种少见但预后严重的皮肤粘膜的疱性疾病。本病早期病损常见于口腔粘膜。所以,口腔科临床对其早期诊断起着重要的作用。例1:女,58岁,76年11月13日初诊,三年前装6活动托牙后,局部发生大疱,疱破后形成糜烂面,不久自愈。以后曾两次出现类似损害。近半年因患痢疾后病情加重。皮肤及外阴均发生大疱,痒甚。口腔溃疡加多且疼痛,有虫爬感,影响进食。在某院诊断为口炎而住院。静脉滴注氢化可的松后病情缓解,皮肤病损消失,但口腔病损时轻时重。双侧颊部、舌背、腭部可见多发性大小不等之浅在溃疡,溃疡表面被以黄白色假膜,假膜易被撕脱并极易出血。全身消瘦衰弱。临床考虑为天疱疮。经 Pemphigus vulgaris is a rare but highly prognosed mucocutaneous vesicular disease. Early lesions of the disease common in oral mucosa. Therefore, clinical stomatology plays an important role in its early diagnosis. Example 1: Female, 58 years old, November 13, 2006 Newly diagnosed, three years ago, 6 activities mounted dentures, the local occurrence of bullae blisters after the formation of erosion surface erosion, and soon self-healing. Similar damage has occurred twice since. Nearly six months after suffering from dysentery increased. Skin and vulva are bullous, itchy even. Oral ulcers plus more pain, insects crawling, affecting eating. In a hospital diagnosed as stomatitis and hospitalization. After the intravenous infusion of hydrocortisone, the disease eases and the skin lesions disappear, but the oral lesions are light and heavy. Bilateral cheeks, tongue back, palate visible multiple sizes of shallow ulcers in the ulcer surface was yellow-white pseudomembrane, pseudomembranous easily torn and easily bleeding. Whole body weight loss and weakness. Clinical consideration for pemphigus. through