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本研究的目的在于考察临床实际应用过程中不同输液包装对药液残留量的影响;通过收集2007年9～10月北京大学第三医院外科住院患者输液治疗后的0.9%氯化钠注射液包装(5个品种,共有100 mL、250 mL和500 mL 3种规格),测定其中的药液残留量,并根据患者用药资料进行相关的药物经济学分析。结果表明,各个包装平均残留液量在0.38～4.8 mL的范围内,残留量随原注射液容积增大而增多;其中一种双阀软袋包装的残留量显著低于其它包装(P<0.05),而单阀软袋的残留量相对较高;根据用药资料推算出的残留液相关药费在每年1.5～15万美元之间。可见不同输液包装对药液残留量的多少有显著影响,选择适当的输液包装有利于提高输液治疗的经济性和有效性。
The aim of this study was to investigate the effects of different infusion solutions on the residual volume of drug solution in clinical practice. By collecting 0.9% sodium chloride injection solution after transfusion treatment in hospitalized patients in Peking University Third Hospital from September to October in 2007, (Five varieties, a total of 100 mL, 250 mL and 500 mL three kinds of specifications), determination of the residual liquid medicine, and based on the patient medication information related to the pharmaceutical economics analysis. The results showed that the average residual liquid volume of each package was in the range of 0.38-4.8 mL and the residual volume increased with the volume of the original injection liquid. The residual amount of one kind of double-valve soft bag package was significantly lower than that of other packages (P <0.05 ), While the single valve soft bag residue is relatively high; based on the drug data calculated residual liquid related drugs in the annual 1.5 to 150,000 US dollars. Shows that different infusion packaging on the amount of residual liquid have a significant impact on the choice of appropriate infusion packaging is conducive to improving the economy and effectiveness of infusion therapy.