目的:探讨尿管管腔内置斑马导丝对导尿困难患者的治疗效果观察研究。方法:收集2017年至2021年9月粤北人民医院住院部、门诊、急诊常规导尿困难患者共69例，其中男67例，女2例，年龄55～81岁。其中前列腺增生常规导尿困难患者50例，前尿道狭窄7例，后尿道狭窄3例，后尿道结石2例，女性尿道狭窄2例，包茎引起的尿道外口狭窄2例，尿道损伤2例，阴茎癌导尿困难1例。均采用尿管管腔内置斑马导丝导尿。结果:2例前列腺增生患者常规留置导尿困难改行耻骨上膀胱穿刺造瘘术，其余均通过尿管管腔内置斑马导丝导尿成功，成功率97.1%（67/69）。结论:尿管管腔内置斑马导丝可以明显提高导尿困难患者的留置尿管成功率，是一种安全有效、简单、经济的方法。“,”Objective:To evaluate the therapeutic effect of Indwelling catheters with build-in zebra urological guidewires for patients with difficult urethral catheterization.Methods:Sixty-nine patients with difficult urethral catheterization who were 51-81 years old and treated at Inpatient Department, Clinic, and Emergency Room at Yuebei People\'s Hospital from 2017 to September 2021 were collected, including 67 males and 2 females. The causes of difficult urethral catheterization included benign prostatic hyperplasia (50 cases), anterior urethra stricture (7 cases), posterior urethra stricture (3 cases), posterior urethra calculus (2 cases), female urethral orifice stricture (2 cases), urethral external orifice stricture resulted from phimosis (2 cases), urethral injury (2 cases), and difficult urethral catheterization resulted from carcinoma of penis (1 case). All the patients were indwelled catheters with build-in zebra urological guidewires.Results:All but 2 cases successfully finished urethral catheterization via catheters with build-in zebra urological guidewire in lumens; the 2 failure cases with benign prostatic hyperplasia underwent percutaneous suprapubic cystostomy instead. The total success rate was 97.1% (67/69).Conclusions:Catheter with build-in zebra urological guidewire in lumen Indwelling catheters with build-in zebra urological guidewires for patients with difficult urethral catheterization can significantly increase the success rate. It is a simple, safe, effective, and economical method.