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近年来,有些学者认为80%的急性心肌梗塞患者使用冠状动脉内灌注链激酶能使闭塞的冠状动脉再通。验证这一疗法的最好途径是显示受损心肌区的左室功能出现好转。本文探索判断这一局部心肌改善的检查方法。方法:31例急性穿壁性心肌梗塞患者,男性27例,女性4例,平均年龄52岁(28～72岁)。所有患者均在胸痛发作三小时内住院,在 ST 段抬高的导联中没有异常的 Q 波,也没有陈旧性的穿壁性心肌梗塞。诊断急性心肌梗塞后立即送至心导管室。先于闭塞的冠状动脉内注入~(201)铊0.3～0.5毫居里,接着滴注链激酶2,000～4,000单位/分,用移动式带有高分辨准直器的 r 照相机,进行右前斜位30°和左前斜位显象。血管再通或链激酶达到最大剂量(25万单位)后30～45分钟再注射~(201)铊0.3～0.5毫居里。
In recent years, some scholars believe that 80% of patients with acute myocardial infarction using coronary perfusion with streptokinase can make occlusion of the coronary recanalization. The best way to validate this therapy is to show improvement in left ventricular function in the impaired myocardium. This article explores and examines how this local myocardial improvement test can be performed. Methods: Twenty-one patients with acute transmural myocardial infarction were 27 males and 4 females, with an average age of 52 years (28-72 years). All patients were hospitalized within three hours of onset of chest pain and had no abnormal Q waves in the leads of ST elevation and no old transmyocardial infarction. Immediate diagnosis of acute myocardial infarction sent to the cardiac catheterization room. Prior to the occlusion of coronary artery injection of ~ (201) thallium 0.3 ~ 0.5 millicuries, and then streptokinase streptomycin 2,000 ~ 4,000 units / min, with a mobile high resolution collimator r camera, right anterior oblique 30 ° and left anterior oblique imaging. Reperfusion or streptokinase reached the maximum dose (250,000 units) 30 to 45 minutes after the injection of ~ (201) Thallium 0.3 ~ 0.5 millicuries.