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目的利用等离子体增强化学气相沉积(plasma enhanced chemical vapor deposition,PECVD)技术,在不同粗糙度医用钛合金表面制备类金刚石薄膜(diamond-like carbon film,DLC),并对类金刚石薄膜的膜-基结合力、电化学腐蚀行为及生物学行为进行研究,探索基底材料喷砂预处理对于表面制备的类金刚石薄膜是否是一种有效改性方法。方法通过不同粒度的Al2O3在一定条件下喷砂钛合金表面,制备出不同粗糙度表面的钛合金片,采用PECVD技术在其表面制备类金刚石薄膜。通过扫描电子显微镜、X-射线光电子能谱仪、拉曼光谱仪、接触角测量仪、表面性能测试仪和电化学方法检测各组样品的物理化学性能表征;利用MTT比色法、荧光染色法进行薄膜表面生物学行为的评价。结果将DLC沉积在喷砂预处理的钛合金表面,可以明显增强类金刚石的膜-基结合力,最高达到45N;耐腐蚀性研究中,表面沉积DLC的钛合金实验组腐蚀电位均正向大于未沉积DLC的钛合金组(P<0.05);生物学行为研究中,在60#Al2O3喷砂处理钛合金表面沉积DLC的S60实验组细胞增殖状况最佳,明显大于未喷砂S0组(P<0.05)。结论将钛合金基底喷砂预处理后沉积DLC,可以提高类金刚石薄膜的膜-基结合力、耐腐蚀性及生物相容性,是一种有效的医用钛合金表面改性方法,具有潜在的临床应用价值。
OBJECTIVE To prepare diamond-like carbon film (DLC) on medical titanium alloy with different roughness by plasma enhanced chemical vapor deposition (PECVD) Binding force, electrochemical corrosion behavior and biological behavior were studied to explore whether the pretreatment of the substrate material for diamond-like carbon surface preparation is an effective modification method. Methods Titanium alloy flakes with different surface roughness were prepared by blasting the surface of titanium alloy under different conditions with different particle sizes. DLC films were prepared on the surface by PECVD. The physico-chemical properties of each sample were characterized by scanning electron microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, contact angle measurement, surface properties tester and electrochemical method. MTT colorimetry and fluorescence staining Evaluation of the biological behavior of the membrane surface. Results The deposition of DLC on the surface of pretreated titanium alloy by blasting can obviously enhance the film-base bonding strength of diamond-like material up to 45N. In the corrosion resistance study, the corrosion potential of the DLC-treated titanium alloy on the surface is positively In the biological behavior study, the cell proliferation status of the experimental group S60 deposited with DLC on the surface of 60 # Al2O3 blast-treated titanium alloy was the best, which was significantly higher than that of the non-gritted S0 group (P <0.05) <0.05). Conclusion Pretreatment of titanium alloy substrate by sandblasting deposited DLC can improve the film-based bonding, corrosion resistance and biocompatibility of diamond-like carbon films. It is an effective method for surface modification of medical titanium alloy with potential Clinical application value.