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目的观察曲美布汀治疗肠易激综合征的临床效果。方法将2009年1月—2011年12月接受治疗的肠易激综合征患者64例,随机分为实验组和对照组各32例。实验组患者口服曲美布汀胶囊治疗,对照组则口服维生素B1和谷维素治疗,两组均治疗4周。对比两组疗效及不同症状的缓解状况。结果实验组总有效率87.50%;对照组总有效率53.13%。两组比较差异有统计学意义(P<0.05)。结论应用曲美布汀治疗肠易激综合征效果优于服用维生素B1和谷维素的治疗效果,值得临床推广。
Objective To observe the clinical efficacy of trimebutine in the treatment of irritable bowel syndrome. Methods Sixty-four patients with irritable bowel syndrome who were treated from January 2009 to December 2011 were randomly divided into experimental group (32 cases) and control group (32 cases). Patients in the experimental group were treated with oral trimebutine capsules, while those in the control group were treated with vitamin B1 and oryzanol. Both groups were treated for 4 weeks. The curative effect and the relief of different symptoms were compared between the two groups. Results The total effective rate was 87.50% in the experimental group and 53.13% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion Trimebutine treatment of irritable bowel syndrome is superior to the effect of taking vitamin B1 and oryzanol, worthy of clinical promotion.