论文部分内容阅读
目的:通过观察冠心病(CHD)患者的甲襞微循环、血液流变学指标、血脂及血糖的变化,为及早诊断、治疗及预后判断提供依据。方法:确诊为CHD的患者156例进行甲襞微循环、血液流变学、血脂及血糖等进行检测。结果:与50例正常人相比较,CHD患者甲襞毛细血管数减少、交叉、畸形管襻增多,输入支变细、输出支和乳头下静脉丛扩张、血流速度减慢伴红细胞聚集;全血黏度、血浆黏度、红细胞压积、血沉、纤维蛋白原、血小板黏附性和聚集性增加;总胆固醇、三酰甘油、血糖增高,高密度脂蛋白胆固醇降低;并发有高血压病、糖尿病、高脂血症的CHD患者的甲襞微循环、血液流变性明显异常。结论:CHD患者的甲襞微循环、血液流变性、血脂、血糖明显异常;并发有高血压病、糖尿病、高血脂症的CHD患者甲襞微循环、血液流变性异常更为严重。
Objective: To observe the changes of nailfold microcirculation, hemorheology index, blood lipid and blood glucose in patients with coronary heart disease (CHD) to provide evidence for early diagnosis, treatment and prognosis. Methods: A total of 156 patients diagnosed as CHD were tested for microcirculation of formazan, hemorrheology, blood lipids and blood glucose. Results: Compared with 50 normal subjects, the number of capillaries in CHD patients was decreased, the number of cross and deformity was increased, the input branch was thinner, the output branch and the papillary venous plexus dilated and the blood flow velocity was slower with erythrocyte aggregation. Blood viscosity, plasma viscosity, hematocrit, ESR, fibrinogen, platelet adhesion and aggregation increased; total cholesterol, triglycerides, elevated blood glucose, high density lipoprotein cholesterol decreased; complicated by hypertension, diabetes, high Hypercholesterolemic CHD patients with nailfold microcirculation, hemorheology significantly abnormal. Conclusion: The thyroid microcirculation, hemorrheology, blood lipid and blood sugar in patients with CHD are obviously abnormal. In patients with CHD complicated by hypertension, diabetes mellitus and hyperlipidemia, the microcirculation of nail polish and hemorrheology are even more serious.