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总结了１年内该院胃镜检查４０８２例次中符合研究标准的２１６例胃溃疡（ＧＵ）患者与１０９例胃粘膜无异常者（对照组），对其幽门螺杆菌（ＨＰ）感染进行了若干情况研究，结果显示ＧＵ组ＨＰ感染率为８４７２％，与胃粘膜无异常组ＨＰ感染率４３１２％相比有显著差异（Ｐ＜０．０１），说明ＨＰ在ＧＵ发病中其重要作用。同时发现，随ＧＵ个数增加ＨＰ感染率升高，但无统计学上的显著差异（Ｐ＞０．０５），胃底至幽门各个部位ＧＵ组ＨＰ感染显著高于贲门组（Ｐ＜０．０１），而其他各组之间无显著差异（Ｐ＞０．０５）。此外，对于ＧＵ周边粘膜有或无蒌缩、肠化和／或异型增生者ＨＰ感染率情况比较，两组之间有显著差异（Ｐ＜０．０１）。
216 cases of gastric ulcer (GU) and 109 cases of gastric mucosa without abnormalities (control group) were enrolled in 4082 cases of gastroscopy in this hospital in one year. Some cases of HP infection were analyzed The results showed that the infection rate of HP in GU group was 84.72%, which was significantly different from the HP infection rate of 43.12% in gastric mucosa abnormal group (P <0.01), indicating that HP plays an important role in the pathogenesis of GU . At the same time, it was found that HP infection rate increased with the number of GU, but there was no significant difference (P> 0.05). HP infection in GU group was significantly higher than that in cardia group (P <0. 01), while no significant difference between the other groups (P> 0.05). In addition, there was a significant difference (P <0.01) between the two groups for HP prevalence in mucosal mucosa with or without constriction, intestinal metaplasia and / or dysplasia.