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抗激素是指在分子水平上特异性阻断激素与受体的结合而抑制激素的药物作用.在癌细胞中性激素受体的浓度比正常细胞高,因此可以用性甾体激素拮抗剂治疗激素依赖性癌,并已获得成功.RU486:一种抗孕激素和抗有丝分裂的药物甾体激素类似物RU486分别与孕激素受体(PR)和糖皮质激素受体(GCR)反应强烈但不产生效应的相互作用,阻止孕激素和糖皮质激素的作用,并可终止早期妊娠.该拮抗剂是
Anti-hormone refers to the molecular level of specific inhibition of hormone binding to the receptor and inhibit the role of hormones in the cancer cells in the concentration of sex hormone receptors higher than normal cells, it can be steroid hormone antagonist hormone therapy Dependent cancer and has been successful.RU486: RU486, an antiprogestin and anti-mitotic drug steroid hormone analogue, strongly reacted with progesterone receptor (PR) and glucocorticoid receptor (GCR), respectively, but did not produce Effect of the interaction, to prevent the role of progesterone and glucocorticoid, and termination of early pregnancy.The antagonist is