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一氧化氮(nitri oxide,NO)是人体内一种生物活性分子。近年的研究表明,它与多种恶性肿瘤的发生、发展密切相关。肿瘤组织中的NO主要由诱导型一氧化氮合酶(iducible nitric oxide synthase,iN-OS)催化合成,本文仅就iNOS与脑胶质瘤的关系作一综述。1 NOS的分类及iNOS的调节1.1 NO
Nitric oxide (NO) is a kind of bioactive molecule in human body. Recent studies have shown that it is closely related to the occurrence and development of many malignant tumors. The NO in tumor tissue is mainly catalyzed by iNOS. The relationship between iNOS and glioma is only reviewed in this paper. 1 NOS classification and regulation of iNOS 1.1 NO