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目的 :提示对肾癌进行血管内介入治疗的重要性的认识 ,探索无水酒精—碘化油药物乳剂经导管血管内栓塞治疗中晚期肾癌的方法及临床效果。方法 :本组肾癌 14例 ,男性 9例 ,女性 5例 ;年龄 31～ 74岁 ,平均 5 7岁 ;临床上无痛性血尿 12例 ,后均经手术及病理证实为肾透明细胞癌 ;右肾 6例 ,左肾 8例。常规行肾动脉造影 :患侧肾动脉灌注化疗加无水酒精—碘化油药物乳剂动脉栓塞。结果 :14例肾癌中 ,肾动脉造影显示血供丰富为 10例 ,表现为患侧肾动脉主干增粗 ,动脉期显示血管变粗扭曲、紊乱、血管呈网状改变、血管移位、包绕征象 ;实质期肿瘤染色 ;肿瘤内部分无血管 2例 ;内部可见紊乱的血管 1例 ;少血供 1例 ,仅仅表现为血管移位、扭曲、肿瘤内部无血管、实质期无肿瘤染色。常规化疗加 1:1无水酒精—碘化油药物乳剂配成混合液 ,再加入平阳霉素、阿霉素配成的乳剂 12～ 2 5ml进行肾动脉栓塞 ,栓塞后表现为症状减轻、肿瘤血供中断、体积缩小及肿瘤碘化油聚集。结论 :无水酒精—碘化油药物乳剂栓塞治疗中晚期肾癌不失为一种安全、有效、方便的方法
Objective: To suggest the importance of endovascular interventional therapy for renal cell carcinoma and to explore the method and clinical effect of transcatheter arterial embolization of anhydrous alcohol-iodinated oil emulsion in advanced stage renal cell carcinoma. Methods: The group of renal cell carcinoma in 14 cases, 9 males and 5 females; aged 31 to 74 years, mean 57 years; clinically painless hematuria in 12 cases, both after surgery and pathology confirmed renal clear cell carcinoma; Right kidney in 6 cases, left kidney in 8 cases. Routine renal artery angiography: ipsilateral renal artery perfusion chemotherapy plus anhydrous alcohol - iodized oil emulsion drug arterial embolization. Results: Among the 14 cases of renal cell carcinoma, renal artery angiography showed that the blood supply was plentiful in 10 cases. The main artery of the ipsilateral renal artery was thickened. In the arterial phase, the blood vessels became rough, distorted, the reticular vessels changed, the vessels were displaced, Signs; parenchymal tumor staining; 2 tumor-free internal parts of the tumor; 1 internal vascular disorder seen; less blood supply in 1 case, showing only vascular displacement, distortion, tumor-free internal blood vessels, no substantial tumor staining. Routine chemotherapy plus 1: 1 anhydrous alcohol - iodized oil drug emulsion dubbed the mixture, followed by Pingyangmycin, doxorubicin dubbed the emulsion 12 ~ 25ml renal artery embolism, embolization showed symptoms, the tumor Blood supply interruption, volume reduction and tumor iodized oil accumulation. Conclusion: Anhydrous alcohol - iodized oil emulsion embolization in the treatment of advanced renal cancer after all, is a safe, effective and convenient method