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本文报告多发性梗塞性痴呆(MID)45例,轻度痴呆26例,占57.8%,中度痴呆15例,占33.3%,重度痴呆4例,占8.9%。CT扫描发现梗塞灶130个,平均2.8个。梗塞灶体积>10ml者14例;4～10ml者18例;小于4ml者13例。梗塞灶部位以基底节、皮质下白质、丘脑、内囊多发性梗塞多见。基底节梗塞产生痴呆者病灶比皮层下梗塞者小,其体积常<4ml。伴有多发性皮质下病变的丘脑梗塞多见,有智能障碍,而少见于无痴呆的多梗塞病人。本文资料推测梗塞容积<50ml时,痴呆综合征与脑萎缩明显相关。
This article reports 45 cases of multiple infarct dementia (MID), 26 cases of mild dementia (57.8%), 15 cases of moderate dementia (33.3%) and 4 cases of severe dementia (8.9%). There were 130 infarcted lesions on CT scan with an average of 2.8. Infarct volume> 10ml in 14 cases; 4 ~ 10ml in 18 cases; less than 4ml in 13 cases. Infarct site to the basal ganglia, subcortical white matter, thalamic, internal capsule multiple infarction more common. Basal infarction in patients with dementia lesions than small subcortical infarcts, the volume often <4ml. With multiple subcortical lesions of the thalamus more common, with mental retardation, and rare in non-demented multi-infarct patients. This article speculates that infarct volume <50ml, dementia syndrome and brain atrophy significantly related.