周围型肺癌病灶位于肺野外周,B超引导或在X射线、CT下经皮肺穿刺活检为其主要确诊手段。随着纤维支气管镜(纤支镜)检查技术的不断提高,目前已成为周围型肺癌另一种非常必要而有效的诊断方法。然而,与中心型肺癌镜下特征不同,周围型肺癌间接征象远较直接征象多见,主要表现为黏膜的浸润、充血水肿、糜烂、管腔狭窄,但镜下正常的比率高达50%,诊断较为困难[1,2]。液基细胞学检测技术早期应用于宫颈癌的筛查,近年来该技术不断 Peripheral lung cancer lesions located in the peripheral lung field, B-guided or X-ray, CT percutaneous pulmonary biopsy as its main means of diagnosis. With the continuous improvement of fiberoptic bronchoscopy (bronchoscopy), it has become another very necessary and effective diagnostic method for peripheral lung cancer. However, unlike central microscopic lung cancer, the indirect signs of peripheral lung cancer are far more common than direct signs, mainly mucosal infiltration, congestion and edema, erosions, stenosis, but up to 50% of normal under the microscope, the diagnosis More difficult [1,2]. Liquid-based cytology early detection of cervical cancer screening in recent years, the technology continues