氨甲喋呤(MTX)是一种较好的治疗严重银屑病的药物,但具有一系列的副作用,其中,最严重的是肝纤维化和肝硬化。有报道,肝活检发现的发病率高达10%,死亡率为0.014%。动态肝闪烁法(DHC)检查是一种简单、非损伤性技术,可以提供稳定的、可重复的结果,而不受观察者主观的影响。肝脏具有二重血液供应:高压动脉系统和低压肝门静脉系统。MTX 损害肝后,后者极易受肝结 Methotrexate (MTX) is a good drug for the treatment of severe psoriasis but has a number of side effects, the most serious of which are liver fibrosis and cirrhosis. It has been reported that the incidence of liver biopsy found up to 10%, the mortality rate was 0.014%. Dynamic Hepatic Scintigraphy (DHC) is a simple, non-invasive technique that provides stable, repeatable results without the subjective influence of observers. The liver has a dual blood supply: the high-pressure arterial system and the low-pressure hepatic portal vein system. MTX damage the liver, the latter vulnerable to liver node