胃肠道的原发性何杰金氏病是一种少见疾病,而食道的原发性何杰金氏病则更极少见,文献中尚无肯定的报导。本文作者报导一例30岁男性患者,主要症状是5个月来进行性吞咽困难和饮酒后胸骨后疼痛。首次就诊时发现病损在食道右前方胸腔入口处,为大约6×3厘米大小的包块,切除包块病理组织学检查,发现肌纤维广泛变性伴炎纲胞浸润,偶见胞浆丰富 Gastrointestinal primary Hodgkin’s disease is a rare disease, and esophageal primary Hodgkin’s disease is even rarer, and there are no positive reports in the literature. The authors report a 30-year-old male patient whose main symptom was dysphagia and poststernal pain after drinking for 5 months. At the first visit, it was found that the lesion was at the entrance of the thoracic cavity at the right front of the esophagus. It was a mass of approximately 6 × 3 cm. Histopathological examination of the mass was performed. The extensive degeneration of myofibers was associated with inflammatory cell infiltration. Occasionally, cytoplasm was abundant.