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[Objective]To investigate the effective component content and the antioxidant activity of the peels of Poria cocos(Schw.)Wolf,and to provide references for the application of P.cocos peels in the processing of high-value health food.[Methods]With the triterpenes methanol extracts of P.cocos peels as the research materials and ursolic acid as the reference substances,the antioxidant activity in vitro was evaluated by colorimetric method and chemiluminescence method.[Results]The percentage content of triterpenes in P.cocos peels was1.58%.Triterpenes in P.cocos peels could effectively remove the superoxide anion free radicals(O-2·),hydroxyl free radicals(·OH)and hydrogen peroxide(H2O2).And their IC50values were 1.01,0.91 and 0.87 mg/mL,respectively.There were certain dose dependence relationship between scavenging rate and concentration.In vitro antioxidant test showed that triterpenes in P.cocos peels could restrict the erythrocyte hemolysis of chicken and had good scavenging effects on the MDA generation during the lipid peroxidation of mice liver.[Conclusions]The antioxidant activity of crude triterpenes in P.cocos peels was comprehensively evaluated.It was verified that the triterpenes had significant antioxidant activity.Effects of the triterpenes treatment groups were superior to the effects of ursolic acid methanol solution.Among them,1.58mg/mL triterpenes methanol solution had the most significant inhibitory effects.
[Objective] To investigate the effective component content and the antioxidant activity of the peels of Poria cocos (Schw.) Wolf, and to provide references for the application of P.cocos peels in the processing of high-value health food. [Methods] With the triterpenes methanol extracts of P.cocos peels as the research materials and ursolic acid as the reference substances, the antioxidant activity in vitro was evaluated by colorimetric method and chemiluminescence method. [Results] The percentage content of triterpenes in P.cocos peels was1 .58% .Triterpenes in P.cocos peels could effectively remove the superoxide anion free radicals (O-2 ·), hydroxyl free radicals (· OH) and hydrogen peroxide (H2O2) .And their IC50 values were 1.01, 0.91 and 0.87 mg / mL, respectively. There was certain dose dependence relationship between scavenging rate and concentration. In vitro antioxidant test showed that triterpenes in P. cocos peels could restrict the erythrocyte hemolysis of chicken and had good scavenging effects o n the MDA generation during the lipid peroxidation of mice liver. [Conclusions] The antioxidant activity of crude triterpenes in P.cocos peels was comprehensively as. It was verified that the triterpenes had significant antioxidant activity. Effects of the triterpenes treatment groups were superior to the effects of ursolic acid methanol solution. Among them, 1.58 mg / mL triterpenes methanol solution had the most significant inhibitory effects.