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目的观察抗氧自由基治疗对癫患者脑电图和发作频数的影响。方法选择2009-01—2012-05于我院神经内科就诊并被诊断为癫患者63例,将所有入选患者按奇数、偶数分为对照组31例和治疗组32例,对照组采用基础抗癫治疗,治疗组在对照组基础上给予抗氧自由基治疗(维生素C、E)。治疗3个月后进行疗效对比。结果治疗组显效21例,有效5例,改善4例,总有效率93.7%;对照组显效15例,有效3例,改善2例,总有效率64.5%,2组总有效率比较差异有统计学意义(P<0.01)。结论抗自由基治疗能够增强抗癫基础治疗的效果,减少癫发作次数和放电频数,疗效显著,可在临床广泛使用。
Objective To observe the effect of antioxidant free radical therapy on electroencephalogram and frequency of seizures in epileptic patients. Methods Sixty-three patients with epilepsy who were diagnosed as neurological department in our hospital from January 2009 to June 2012 were enrolled in this study. All patients were divided into two groups according to the odd and even numbers: control group (31 cases) and treatment group (32 cases) Epilepsy treatment, the treatment group on the basis of the control group given antioxidant free radical therapy (vitamin C, E). After 3 months of treatment efficacy comparison. Results In the treatment group, 21 cases were markedly effective, 5 cases were effective, 4 cases were improved, and the total effective rate was 93.7%. In the control group, 15 cases were markedly effective, 3 cases were effective, 2 cases were improved, and the total effective rate was 64.5% Significance (P <0.01). Conclusion Anti-free radical therapy can enhance the effect of anti-epileptic basal therapy, reduce the number of epileptic seizures and discharge frequency, with significant curative effect and can be widely used clinically.