甲基三唑安定(Alprazolam)为一种新型苯氮(艹卓)类药物,具有抗焦虑、抗抑郁、镇静、催眠和解痉作用。因其治疗谱较广,毒副作用较轻,故在国外得到较广泛应用。我国已由北京医科大学药学院与济南制药厂联合制成并生产。甲基三唑安定又名阿普唑仑,化学名称为8-氯-1-甲基-6-苯基-4H-[1,2,4-]-三唑[4,3-a][1,4-苯并二氮杂(艹卓)]。分子式为C_(17)H_(13)ClN_4,分子量308.77。为白色或微红色结晶粉末。能溶于氯仿、丙酮和乙醇,不溶于水和乙醚。熔点为227～ Alprazolam is a new class of benzodiazepines that have anti-anxiety, anti-depressant, sedative, hypnotic and antispasmodic effects. Because of its treatment spectrum is broader, less toxic side effects, it is more widely used abroad. China has been made and produced by Beijing Medical University and Jinan Pharmaceutical Factory. Methyltriazoline is also known as alprazolam, with the chemical name 8-chloro-1-methyl-6-phenyl-4H- [1,2,4] -triazolo [4,3-a] 1,4-benzodiazepine]. Molecular formula C_ (17) H_ (13) ClN_4, molecular weight of 308.77. White or reddish crystalline powder. Soluble in chloroform, acetone and ethanol, do not dissolve in water and ether. Melting point is 227 ~