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目的为了解EB病毒显性感染在不同人群中的差别。方法将270例疑似EB病毒感染者分成儿童组及成人组,采用ELISA方法检测血清EB-VCAIgA、EB-VCAIgG、EB-VCAIgM;并对结果进行相关统计学分析。结果128例儿童中EB病毒显性感染23例(阳性率18.0%);142例成人中EB病毒显性感染8例(阳性率5.6%);儿童EB病毒显性感染高于成人(χ2=16.48,P<0.05)。成人EB病毒显性感染患者中VCA-IgG阳性率高于儿童(χ2=15.06,P<0.05)。结论儿童比成人更易出现EB病毒显性感染。
Purpose To understand the differences in different groups of people with EBV dominant infection. Methods Two hundred and seventy cases of suspected Epstein-Barr virus (EBV) infection were divided into pediatric group and adult group. Serum EB-VCAIgA, EB-VCAIgG and EB-VCAIgM were detected by ELISA. Statistical analysis of the results was performed. Results Of the 128 children, 23 cases were positive for Epstein-Barr virus (positive rate, 18.0%). In 142 adults, 8 cases were positive for Epstein-Barr virus (positive rate, 5.6%). The EBV infection in children was higher than that in adults , P <0.05). The positive rate of VCA-IgG in patients with adult Epstein-Barr virus dominant infection was higher than that in children (χ2 = 15.06, P <0.05). Conclusion Children are more likely to develop Epstein-Barr virus dominant infection than adults.