霍乱B亚单位-菌体菌苗(BS-WC)系由1mg BS和1×10~(11)WC组成;安慰剂系经加热杀死的相同浓度大肠杆菌K12株。将63,498名2～15岁孟加拉国儿童和15岁以上的妇女随机分成3组,以随机双盲形式分别接种BS-WC、WC或安慰剂,每人3剂,同时口服2.8%碳酸氢钠/1.1%柠檬酸缓冲液,剂量为2～4岁者服40ml,5～11岁者服75ml,11岁以上者服155ml。菌苗保护水平以其保护效力(PE)表示,公式为: The cholera B subunit-bacterial cell vaccine (BS-WC) consisted of 1 mg BS and 1 × 10-11 WC; placebo was heat-killed K12 strain of the same concentration. 63,498 Bangladeshi children aged 2 to 15 years and women over the age of 15 were randomly assigned to 3 groups and were randomized to receive 3 doses of BS-WC, WC or placebo in a randomized, double-blind fashion with 2.8% sodium bicarbonate / 1.1% citrate buffer, dose of 2 to 4 years old service 40ml, 5 to 11 years old service 75ml, 11 years of age service 155ml. The level of bacterin protection is expressed in terms of its protective effect (PE) as: