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世界上一些地方(中国、哈萨克、德国、波多黎各和库拉索岛)食管恶性肿瘤的发病率很高,可能与外在的因素如大量抽烟、饮酒、亚硝胺、苯酚和单宁有关。作者发现热损伤可能在人的病理学上起重要作用。实验证明,当食管粘膜的完整性受损,可引起食管的恶性肿瘤。材料和方法:Wistar 大鼠120只(雌雄兼有)分为4组、对照组、单独热水处理组、甲基硝基亚硝基胍(MNNG)处理组,热水和MNNG 联合处理组,每组30只。单独用热水处理组,通过金属管将3 ml
The incidence of esophageal malignancies is high in some parts of the world (China, Kazakhstan, Germany, Puerto Rico and Curaçao) and may be related to extrinsic factors such as heavy smoking, alcohol consumption, nitrosamines, phenol and tannin. The authors found that thermal damage may play an important role in human pathology. Experiments show that when the integrity of esophageal mucosa damage can cause esophageal cancer. MATERIALS AND METHODS: 120 Wistar rats (male and female) were divided into 4 groups: control group, single hot water treatment group, MNNG treatment group, hot water treatment group and MNNG treatment group, Each group of 30. Separately with hot water treatment group, through a metal tube 3 ml