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本课题进行了酵母菌菌丝蛋白的急性毒性试验和亚急性毒性试验（９０天喂养）。结果：菌丝蛋白急性毒性属于无毒级范围，亚急性毒性显示菌丝蛋白在饲料中添加量达４０％时，对大白鼠有一定不良影响，主要表现为雄性大鼠生长缓慢、摄饲效率低、肾体比增大，雌性大鼠的肝体比、肾体比增大。亚急性毒性试验的最大无作用剂量（ＭＮＬ），菌丝蛋白在饲料中添加量为２０％（相当于２００ｇ菌丝蛋白／ｋｇ饲料），故添加量应在１０％～１５％为宜。
This topic carried out the acute toxicity test of yeast mycelium protein and subacute toxicity test (90 days feeding). Results: The acute toxicity of mycelium protein belonged to the non-toxic grade range. Subacute toxicity showed that when mycelium protein was added to the feed by 40%, the mycelial protein had certain adverse effects on the rats. The main manifestations were the slow growth of male rats, the feeding efficiency Low, the ratio of kidney increased, the ratio of liver to body than female rats, increased renal ratio. Submaximal toxicity test of the maximum non-acting dose (MNL), mycelium in the feed amount of 20% (equivalent to 200g mycelium protein / kg feed), it should be added in an amount of 10% to 15% is appropriate.