癌症的发生不但与癌基因激活、抑癌基因失活、代谢酶基因异常有关,与修复酶基因可能也有关系,因而也日益受到关注。DNA修复酶基因在维持DNA的稳定性中发挥着重要作用,若其出现异常,则不能正确地识别及修复DNA的损伤,最后可能导致肿瘤的发生。 The occurrence of cancer is not only related to the activation of oncogenes, inactivation of tumor suppressor genes and gene abnormalities of metabolic enzymes, but also to the repair of the enzyme genes, which is also attracting more and more attention. DNA repair enzyme gene plays an important role in maintaining the stability of DNA, if it is abnormal, it can not correctly identify and repair DNA damage, which may eventually lead to the tumor.