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目的探讨75岁以上老年急性心肌梗死的静脉溶栓的安全性及疗效。方法选取从2008年1月至2011年10月在我院心内科住院治疗,年龄≥75岁(75～84岁)急性STEMI患者42例,给予尿激酶减量(120万单位)溶栓同时选取因各种原因未行溶栓治疗的急性STEMI患者43例,观察两组的临床疗效。结果高龄溶栓组在死亡率、心力衰竭发生率、血管再通的发生率均与对照组有差异。结论高龄急性STEMI患者在严格掌握适应症的情况下采取尿激酶减量(120万单位)溶栓治疗是安全有效的。
Objective To investigate the safety and efficacy of intravenous thrombolysis in elderly patients with acute myocardial infarction over 75 years old. Methods Forty-two patients with acute STEMI who were hospitalized in Department of Cardiology of our hospital from January 2008 to October 2011 were enrolled in this study. Concurrent thrombolysis with urokinase (1.2 million units) 43 cases of acute STEMI without thrombolysis for various reasons, the clinical efficacy of the two groups were observed. Results The incidence of death, heart failure and recanalization in elderly thrombolysis group were different from those in control group. Conclusions It is safe and effective to take thrombolytic therapy of urokinase (1.2 million units) in elderly patients with acute STEMI under strict control of indications.