心房颤动(Atrial fibrillation AF)是临床上最常见的持续性快速心律失常。其发病率随年龄增长而增加,40岁以下人群发病率约为0.2％～0.3％,60～90岁组发病率增至5％～9％[1]。尽管AF本身不直接危及生命,但快速的心室率可引起血流动力学变化,引起明显症状,尤其可增加发生脑血管栓塞的危险,一直是关注的热点。近年来房颇机制研究中突破性进展有二方面:一是发现肺静脉心房端等局灶起源可引起AF,经射频消融这些异位节律灶可 Atrial fibrillation AF is the most common persistent tachyarrhythmia in clinic. The incidence increases with age, the incidence of people under 40 years of age is about 0.2% to 0.3%, 60 to 90-year-old group increased the incidence of 5% to 9% [1]. Although AF itself is not directly life-threatening, rapid ventricular rate can cause hemodynamic changes, causing obvious symptoms, in particular increasing the risk of cerebrovascular embolism has been a hot spot of concern. In recent years, there are two breakthroughs in the mechanism of Fangpo: First, it is found that the origin of pulmonary venous atrial end can cause AF, ablation of these ectopic rhythm can be RFA