近年研究已证实[1] ,β3 肾上腺素能受体 (β3 ＡＲ)基因在细胞内侧第一个氨基酸环处 ,由于胞嘧啶取代胸腺嘧啶引起 6 4号位密码子色氨酸被精氨酸置换 ,引起该基因变异 ,形成Ｔｒｐ6 4Ａｒｇ等位基因。Ｓａ ｋａｎｅ等[2 ] 在日本人群中的研究表明 ,β3 ＡＲ基因多态性与 2 Recent studies have confirmed [1] that the β3 adrenergic receptor (β3 AR) gene is located at the first amino acid loop in the inner cell and the substitution of cytosine for thymine results in replacement of the codon 44 of tryptophan at codon position 4 with arginine , Causing the gene to mutate to form the Trp6 4Arg allele. Sa kane et al [2] in the Japanese population studies have shown that β3 AR gene polymorphism and 2