临床常用强的松治疗重度Graves眼病,但该疗法有许多副作用。环孢霉素是一种强有力的免疫抑制剂,能改变辅助性T淋巴细胞和某些B淋巴细胞的作用。因而,环孢霉素能干扰细胞和体液自身免疫过程,Bahn认为它对Graves眼病有一定作用。因此,作者进行了一项单盲随机抽样临床试验来比较强的松和环孢霉素治疗的效果、安全性和耐受性。 Clinical commonly used prednisone treatment of severe Graves eye disease, but the therapy has many side effects. Cyclosporine is a potent immunosuppressant that alters the effects of helper T lymphocytes and certain B lymphocytes. Thus, cyclosporine can interfere with cellular and humoral autoimmune processes, Bahn that it has an effect on Graves eye disease. Therefore, the authors conducted a single-blind randomized clinical trial to compare the efficacy, safety and tolerability of prednisone and cyclosporine.