已报告 3—羟—3—甲戊二酰辅酶 A(HMG—CoA)还原酶抑制剂洛伐他汀(Lovastatin)能致毒性非炎性肌病。本文报道1例66岁妇女患者,用不同于洛伐他汀的HMG—CoA还原酶抑制剂巴伐斯丁Pra—vastatin治疗5个月引起了皮肤肌炎综合征。患者入院时,双上肢近端表现严重亚急性肌无力,面、颈、肩、胸和臂出现明显大疮性红斑皮肤损害。血清肌酸激酶水平升高(> It has been reported that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin can cause toxic non-inflammatory myopathy. This article reports a case of 66-year-old woman with a different treatment with lovastatin HMG-CoA reductase inhibitor Pravastatin pravastatin for 5 months caused a skin myositis syndrome. Patients admitted to the hospital, the proximal upper extremity showed severe subacute myasthenia gravis, noodles, neck, shoulders, chest and arm obvious obvious erythema erythema skin damage. Serum creatine kinase levels (>