血容量增加可能是引起柯兴综合征高血压及心钠素(ANH)增高的原因之一。最近有报道,皮质激素可直接作用于大鼠心房组织,刺激 ANH 的产生及分泌。为此,作者研究了柯兴综合征病人 ANH 分泌的水平。18例中男2例,女16例,年龄16～73(平均38±13)岁。12例为柯兴病,6例为肾上腺腺瘤。14例有高血压。全部病人的血钠正常,血钾平均为3.7±0.6mmol/L,5例血钾<3.5mmol/L,血醛固酮为269±127pmol/L,其中2例高于正常。为了解合成糖皮质激素对 ANH 的分泌是否有影响,同时对15例长期使 Increased blood volume may be one of the causes of high blood pressure and atrial natriuretic peptide (ANH) in Cushing’s syndrome. Recently it has been reported that corticosteroids can act directly on the atrial tissue of rats to stimulate the production and secretion of ANH. To this end, the authors studied the level of ANH secretion in patients with Cushing’s syndrome. There were 2 males and 16 females in 18 cases, ranging in age from 16 to 73 (average 38 ± 13) years. Twelve cases were Cushing’s disease and 6 cases were adrenal adenoma. 14 cases of high blood pressure. All patients with normal serum sodium, potassium average of 3.7 ± 0.6mmol / L, 5 cases of serum potassium <3.5mmol / L, serum aldosterone was 269 ± 127pmol / L, of which 2 were higher than normal. In order to understand whether the synthesis of glucocorticoid secretion of ANH is affected, while 15 cases of long-term