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过去,肝功能试验主要狭义地指反映肝细胞代谢功能的试验。随着生化、电泳、免疫等技术的进展,肝功能试验的范围不断扩大。70年代是肝功能试验的全盛时期,至少包括临床酶学、有机阴离子代谢、肝内蛋白合成、胆汁酸代谢、免疫球蛋白合成及肝肿瘤标志物的分泌等,基本上反映了肝细胞、胆道、单核吞噬细胞及肝血流等四个系统功能状态的检查。 80年代以来,由于各种新型器械的问世,肝病检查的手段大大增加。过去无法解决的肝内外胆道管梗阻鉴别问题,通过ERCP及PTC基本上迎刃而解。肝内局限性小病灶,如今通过B型超声、CT、选择性动脉造影或核磁
In the past, liver function tests mainly narrowly reflect the metabolism of liver cells function test. With the progress of biochemical, electrophoretic and immunological technologies, the scope of liver function tests has been expanding. The heyday of liver function tests in the 1970s included, at a minimum, clinical enzymology, organic anion metabolism, intrahepatic protein synthesis, bile acid metabolism, immunoglobulin synthesis, and secretion of liver tumor markers, which basically reflected the hepatocytes, biliary , Mononuclear phagocytes and liver blood flow four system status check. Since the 1980s, due to the advent of a variety of new devices, liver disease inspection means greatly increased. In the past can not solve the identification of intrahepatic and extrahepatic bile duct obstruction by ERCP and PTC basically solved. Small intrahepatic lesions, and now by B-mode ultrasound, CT, selective arteriography or nuclear magnetic