【摘 要】
:
8, 8-Dimethyl-5, 6, 7, 8-tetrahydrophenanthrene-3, 4-dione (3)and 8, 8-dimethyl-2-(1-hydroxy ethyl)-5, 6, 7, 8-tetrahydrophe-nanthrene-3, 4-dione (4), two anal
【机 构】
:
Xinjiang Technical Institute of Physics & Chemistry,Chinese Academy of Sciences,Urumqi,Xinjiang 8300
【出 处】
:
Chinese Journal of Chemistry
论文部分内容阅读
8, 8-Dimethyl-5, 6, 7, 8-tetrahydrophenanthrene-3, 4-dione (3)and 8, 8-dimethyl-2-(1-hydroxy ethyl)-5, 6, 7, 8-tetrahydrophe-nanthrene-3, 4-dione (4), two analogues of the antitumor activetanshinone, were synthesized from anisole. The synthesizedcompounds 3 and 4 were shown to be highly active againstleukemia P-388 cell line as assayed by in vitro MTT method.
8, 8-Dimethyl-5, 6, 7, 8-tetrahydrophenanthrene-3, 4-dione and 8,8- nanthrene-3, 4-dione (4), two analogues of the antitumor activetanshinone, were synthesized from anisole. The synthesized compounds 3 and 4 were shown to be highly active against leukemia P-388 cell line as assayed by in vitro MTT method.
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