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GLP-1主要由正常人体肠道L细胞和中枢神经元分泌的,主要通过调控胰岛素和胰高血糖素的分泌,延缓胃的排空和调节胰岛素的敏感性等途径来调控血糖,是重要的肠促胰岛素。但其除了降糖作用,还可以改善糖尿病引起的神经和心血管系统损伤。临床上中医脑心同治理论在疾病治疗上有了显著的成效,笔者将在这里回顾一下GLP-1对中枢神经及心血管的作用和中医脑心同治理论治疗消渴证的关系。
GLP-1 is mainly secreted by normal human intestinal L cells and central neurons. It is important that GLP-1 regulate blood glucose mainly by regulating the secretion of insulin and glucagon, delaying gastric emptying and regulating the sensitivity of insulin Insulinotropic hormone. However, in addition to its hypoglycemic effect, it can also improve the nervous and cardiovascular system caused by diabetes. Clinical TCM brain with Tongzhi theory in the treatment of disease has a significant effect, I will review here the role of GLP-1 on the central nervous system and cardiovascular function and TCM brain Tongzhi theory on the treatment of Diabetes Syndrome.