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目的探讨人体是否存在尿道膀胱反流及其临床意义。方法首次应用同位素检查方法对９例反复下尿路感染患儿和正常对照组３例儿童进行研究。结果证实人体中尿道膀胱反流（ＵＶＲ）的存在。结论尿道器质或功能性异常所引起的尿流改变及尿道外括约肌（ＥＵＳ）异常收缩是产生ＵＶＲ的重要机制。ＵＶＥ不但能诱发尿道感染（ＵＴＩ），并且是ＵＴＩ迁延不愈的重要因素。
Objective To investigate the existence of urethral bladder reflux in human and its clinical significance. Methods For the first time, three cases of children with recurrent lower urinary tract infection and normal controls were studied by isotope test. The results confirm the presence of urinary bladder reflux (UVR) in the human body. Conclusions Urinary flow changes and abnormal urethral sphincter (EUS) abnormalities caused by urethral abnormalities or functional abnormalities are important mechanisms of UVR. UVE can not only induce urethral infection (UTI), and UTI is an important factor in delayed healing.