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在对５８９８人进行的病毒性肝炎血清流行病学调查分析中，发现接种乙肝疫苗者的丙肝抗体阳性率明显低于未接种人群，５５３名按种过乙肝疫苗者中，抗－ＨＣＶ阳性率为２．５３％，而未接种过乙肝疫苗者的抗－ＨＣＶ阳性率为５．２３％，两组具有非常显著的差异（Ｐ＜０．０１，ＯＲ＝０．３８，９５％可信区间为０．２ｌ～０．６７）。按年龄分层进行分析，结果每个年龄组中接种过乙肝疫苗者的抗－ＨＣＶ阳性率都低于未按种组，在１岁～、１０岁～、３０～５９岁年龄段中抗－ＨＣＶ阳性率在接种和未接种组中分别为１．２％和２．６％，４．４％和５．６％、２．８％和６．１％。疫苗接种次数和疫苗接种率都表现出与抗－ＨＣＶ阳性率之间明显的剂量效应关系。
In the survey of 5 588 seroprevalence of viral hepatitis, we found that the positive rate of hepatitis C antibody in those who were vaccinated with hepatitis B vaccine was significantly lower than that in non-vaccinated population. Among the 553 hepatitis B vaccinated patients, the positive rate of anti-HCV was 2.53% respectively, while the positive rate of anti-HCV in those who did not receive hepatitis B vaccine was 5.23%. There was a significant difference between the two groups (P <0.01, OR = 0.38, 95% confidence interval 0.2l ~ 0.67). Analyzed by age stratification, the positive rate of anti-HCV in each age group vaccinated with hepatitis B vaccine was lower than that of the non-HCV group in the age group of 1 year old, 10 years old, 30 to 59 years old, The positive rate of HCV was 1.2% and 2.6%, 4.4% and 5.6%, 2.8% and 6.1% respectively in vaccinated and non-vaccinated groups. Both the number of vaccinations and the vaccination rate showed a significant dose-response relationship with the anti-HCV positive rate.