在过渡金属催化和有机小分子参与下,α,β-不饱和酮与烯丙醇可顺利地发生Morita-Baylis-Hillman(MBH)反应,生成相应的烯丙基化偶联产物.该MBH反应具有原料易制备、与许多官能团兼容、很好的区域和立体选择性和令人满意的产率.并提出利用六氟异丙醇形成鏻盐和活化烯丙醇的可能机理. Morita-Baylis-Hillman (MBH) reaction of α, β-unsaturated ketone and allyl alcohol can be smoothly carried out with the participation of transition metal catalysis and small organic molecules to generate the corresponding allylated coupling products. The MBH reaction It has the advantages of easy preparation of raw materials, compatibility with many functional groups, good regioselectivity and satisfactory yield, and proposes the possible mechanism of using hexafluoroisopropanol to form phosphonium salt and activate allyl alcohol.