尽管庆大霉素在临床使用中常有不良反应甚至严重不良反应发生,但目前仍为基层医疗单位常用的抗生素。为了更有效更安全地使用此种抗生素,我们建议:①用药前做皮肤过敏试验;②不与其它药物如复方氨基比林、氯霉素等药合用;③一日用量成人以24万U为限,连续用药天数不超过3～5d;④肾功能不全者慎用或不用,必须使用时应作药学监护;⑤婴幼儿禁用。 Although gentamicin often has adverse reactions even serious adverse reactions in clinical use, it is still the commonly used antibiotics in primary medical units. In order to be more effective and safer to use such antibiotics, we recommend: ① do skin allergy test before treatment; ② not with other drugs such as compound aminopyrine, chloramphenicol and other drugs; ③ daily dosage of adults to 240,000 U Limit, the number of consecutive medication does not exceed 3 ~ 5d; ④ renal insufficiency with caution or not, must be used for drug monitoring; ⑤ infants disabled.