蛛网膜下腔出血(SAH)最常见的病因是颅内动脉瘤,其它病因如动静脉畸形、动脉性高血压、肿瘤出血、血液恶病质及某些凝血障碍则很少见。凝血因子Ⅶ(FⅦ),为外源性凝血过程所必需,先天性FⅦ缺乏是一种常染色体隐性遗传,仅在纯合子显型表达,过去关于先天性FⅦ缺乏所致SAH的报道多为儿童。本文报道两例成年女性SAH患者,均经头颅CT确诊,而全脑血管造影都排除颅内血管畸形,凝 Subarachnoid hemorrhage (SAH) is the most common cause of intracranial aneurysms, other causes such as arteriovenous malformations, arterial hypertension, tumor bleeding, blood cachexia and some coagulation disorders are rare. Coagulation factor Ⅶ (FⅦ), essential for the process of exogenous coagulation, congenital deficiency of FⅦ is an autosomal recessive, only in homozygous phenotype, in the past on the congenital FⅦ deficiency caused by SAH mostly child. This article reports two cases of adult female SAH patients were diagnosed by head CT, and all cerebral angiography exclude intracranial vascular malformations, coagulation