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目的:分析妊娠期未足月胎膜早破孕妇发生孕周及病因,为临床处治提供指导。方法:103例未足月胎膜早破孕妇患者按孕周分为两组,对他们的临床资料进行回顾性研究。结果:2组在患者平均年龄及反应感染的血指标没有明显区别,均未提示入院时存在感染。103例PPROM患者破膜孕周主要发生在孕32-36+6周,双胎及生殖系统微生物感染为破膜的主要原因,终止妊娠原因主要为羊水过少。宫颈管微生物培养菌主要为GBS,其余可见的有白色念珠菌,表皮葡萄球菌,弓形虫,及其他厌氧菌。结论:生殖系统炎症尤其是GBS感染是导致未足月胎膜早破的重要原因;双胎也是导致PPROM发尤其是生的高危因素,减少胎膜早破,也有助于降低剖宫产率,改善胎儿结局。
OBJECTIVE: To analyze gestational age and etiology of premature rupture of membranes in pregnant women and provide guidance for clinical treatment. Methods: A total of 103 pregnant women with preterm premature rupture of membranes were divided into two groups according to gestational age, and their clinical data were retrospectively studied. Results: There was no significant difference between the two groups in the mean age of patients and the blood-reaction indexes of infection, which did not suggest the presence of infection at admission. 103 cases of PPROM patients with rupture of gestational weeks occurred mainly in pregnant 32-36 + 6 weeks, twins and reproductive system microbial infection is the main reason for rupture of membranes, termination of pregnancy is mainly due to oligohydramnios. Cervical tube microbial culture bacteria mainly GBS, the remaining visible Candida albicans, Staphylococcus epidermidis, Toxoplasma gondii, and other anaerobic bacteria. Conclusion: Reproductive system inflammation, especially GBS infection, is an important cause of preterm premature rupture of membranes. Twins are also risk factors for PPROM, especially premature rupture of membranes, and also help to reduce cesarean section rate, Improve fetal outcome.